The bomb, which struck a bus and taxi station in the town, also wounded 33 people, some of them seriously, the Britain-based Syrian Observatory for Human Rights reported.
There was no immediate claim of responsibility for the bombing but the Observatory said there had been persistent security incidents in the town since its capture by Turkish troops from the Islamic State group in February 2017.
The town, some 30 kilometres northeast of Syria's second city Aleppo, was one of the westernmost strongholds of the Islamic State group's self-styled "caliphate" which was finally eradicated by US-backed Kurdish forces in eastern Syria in March.
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